Laboratory analysis of 1,4-dioxane

First of all, what is 1.4-dioxane?
 

The chemical substance 1.4-dioxane is a cyclic ether with a molecular weight of 88.1 g/mol (C4H8O2, Chemical Abstracts Service Registry Number 123-91-1) that has many chemical properties. Consumers may encounter this chemical in their everyday products.

In what context do you encounter 1.4-dioxane? 
 

To answer this question, let’s start with the ICH Q3C definition. According to the ICH Q3C, 1,4-dioxane is a residual solvent in pharmaceutical products. They are defined as volatile organic chemicals used or produced in the manufacture of pharmaceutical products or drug substances.

However, it is also found in soils since this liquid is miscible in water. However, this substance is not limited to the environmental and pharmaceutical sector. 

Indeed, you can find 1.4 dioxane in hair shampoos, hand soaps, shower gels…etc. Cosmetic products are regularly tested for 1.4-dioxane in their products.