--- type: "WebPage" title: "PFAS analysis in the laboratory: identifying and quantifying per- and polyfluoroalkyl substances" description: "PFAS analysis: regulatory compliance and chemical characterization What are PFAS? PFAS (Per- and PolyFluoroAlkyl Substances) are a large family (several thousand) of molecules containing at least one highly fluorinated carbon motif (C–F bonds), which is very stable. This stability explains..." resource: "https://filab.fr/en/our-services/our-analysis-services/analysis-per-and-polyfluoroalkylated-substances-pfas/" tags: ["EN", "pll_638f5b0513b0e", "Anaïs DECAUX"] timestamp: "2026-08-25T13:36:41Z" published: "2023-04-19T08:13:35Z" language: "en" author: "bwa" --- # PFAS analysis in the laboratory: identifying and quantifying per- and polyfluoroalkyl substances ## PFAS analysis: regulatory compliance and chemical characterization ### What are PFAS? PFAS (Per- and PolyFluoroAlkyl Substances) are a large family (several thousand) of molecules containing at least one highly fluorinated carbon motif (C–F bonds), which is very stable. **This stability explains their persistence in the environment and often in the body, hence the nickname “forever chemicals”**. These are chemical compounds with anti-adhesive, waterproofing, or high-heat-resistant properties. Per- and polyfluoroalkyl substances ([PFAS](http://www.anses.fr/fr/content/pfas-substances-chimiques-persistantes)) **are now subject to major regulatory restrictions in France and Europe,** affecting many industrial sectors: cosmetics, textiles, plastics processing, coatings, technical materials, industrial equipment, and more. ## FILAB laboratory’s PFAS expertise FILAB is an [independent laboratory specializing in analytical chemistry](https://filab.fr/en/our-services/our-analysis-services/chemical-analysis-laboratory/analytical-chemistry-laboratory.md) and [materials characterization](https://filab.fr/en/our-services/our-analysis-services/laboratory-material-testing.md). We deploy cutting-edge expertise dedicated to trace detection and quantification of substances subject to strict regulatory restrictions. This expertise is applied in particular to complex and heterogeneous matrices, such as polymers, chemical formulations, or industrial fluids.  **Our approach goes beyond simple measurement:**** ** To ensure the reliability of every **PFAS analysis**, our laboratory develops tailor-made multi-technique approaches. We combine complementary methodologies based on high-resolution chromatographic and spectrometric coupling techniques (notably LC-MS/MS). The high performance of our PFAS analysis laboratory ensures:  - Structural elucidation and compound speciation. - Ultra-trace quantification (detection thresholds in the ppb/ppt range). - Detailed interpretation of PFAS presence, whether short- or long-chain molecules, precursors, or their polymeric forms (fluoropolymers). Secure your regulatory compliance efforts and gain a scientifically sound interpretation of your results. ## Our PFAS analysis services Services ### Targeted PFAS Analysis: 20 Substances **Regulatory screening.** Quantitative analysis of 20 representative PFAS among the substances most commonly regulated. Techniques: LC/MS-MS [Analysis by LC-MSMS](https://filab.fr/en/our-technical-resources/altis-lc-msms-analysis.md) Limits of quantification (LoQ) 1 to 10 ppb depending on the matrix What are the needs? - Regulatory status review - Product compliance verification - Supplier control - PFAS pre-audit Services ### Advanced PFAS Analysis: 36 Substances **Cosmetics & complex matrices** Extended quantitative analysis of 36 PFAS, adapted to complex matrices (cosmetics, polymers, coatings, technical materials). Techniques: LC/MS-MS, GC/MS-MS, HC-GC/MS Limits of quantification (LoQ) - 1 to 20 ppb depending on the matrix Specifics: Multi-technique methodology and the possibility of analytical optimization in the event of matrix effects Which sectors? - [Cosmetics](https://filab.fr/en/sectors-of-activity/laboratory-analysis-cosmetics.md) - [Plastics processing](https://filab.fr/en/our-services/our-analysis-services/polymer-materials-analysis-laboratory.md) - Technical textiles - [Surface treatments](https://filab.fr/en/our-services/our-analysis-services/laboratory-surface-characterization/laboratory-analysis-expertise-surface-treatment.md) - [Composite materials](https://filab.fr/en/our-services/our-analysis-services/polymer-materials-analysis-laboratory/laboratory-analysis-composite-material.md) Services ### Total Fluorine Determination **Overall indicator of fluorinated compounds** Total fluorine determination makes it possible to assess the overall presence of fluorinated compounds, including non-targeted PFAS. Techniques: - Combustion + [ion chromatography (IC)](https://filab.fr/nos-moyens-techniques/laboratoire-analysis-chromatographie-ionique/) - Furnace fusion (bead) + IC Regulatory relevance: - Overall evidence in the event of an authority inspection - A guidance tool for additional analysis - Demonstration of compliance with “no fluorine” requirements ### Critical case: polymeric PFAS **Total fluorine> 50 ppm & targeted PFAS <25 ppb?** This suggests the likely presence of polymeric PFAS that cannot be detected by standard targeted methods. **Our solution:**Qualitative screening by **[Pyrolysis GC/MS](https://filab.fr/en/our-technical-resources/py-gc-ms-pyrolysis-gc-ms.md) (Py-GCMS)** **This technique makes it possible to:** - identify signatures of fluorinated polymers - differentiate polymeric PFAS / non-PFAS - provide scientific evidence in the event of an audit or inspection This situation is common in polymeric materials, coatings, membranes, seals, and technical textiles. ### Why choose FILAB? In the face of regulatory changes concerning forever pollutants, relying on a competent **PFAS testing laboratory** is essential. FILAB positions itself as a **PFAS expert laboratory** capable of supporting the chemical, cosmetics, and environmental sectors. With a diverse, state-of-the-art analytical platform ([GC-MS](https://filab.fr/nos-moyens-techniques/laboratoire-analysis-chromatographie-gc-ms/), [LC-MS\/MS](https://filab.fr/en/our-technical-resources/altis-lc-msms-analysis.md), CI, Py-GCMS…), the FILAB laboratory adapts its per- and polyfluoroalkyl substance analysis methods according to the matrix to be studied (liquid, solid, powders…). PFAS testing in finished cosmetic products (emulsions, [makeup](https://filab.fr/en/our-services/our-analysis-services/laboratory-analysis-heavy-metal/laboratory-analysis-heavy-metals-make-up.md) products, lotions...) and cosmetic raw materials Total fluorine testing by combustion ion chromatography (CIC) Quantification of fluorinated molecules by LC-MS [Search for traces of elemental impurities](https://filab.fr/en/our-services/our-analysis-services/laboratory-detection-identification-impurities.md) (contamination, pollution, residue…) The [analysis can be validated according to ICH Q2](https://filab.fr/en/our-services/our-expertise-services/laboratory-analytical-method-validation/validation-of-laboratory-analysis-methods-according-to-the-ich-q2-standard.md) [TFA analysis](https://filab.fr/en/our-services/our-analysis-services/analysis-per-and-polyfluoroalkylated-substances-pfas/tfa-laboratory-analysis.md) [Research into PFAS alternatives](https://filab.fr/en/our-services/our-analysis-services/analysis-per-and-polyfluoroalkylated-substances-pfas/pfas-substitutes-looking-for-alternatives-in-the-laboratory.md) Screening by [LC-MS](https://filab.fr/en/laboratory-mass-spectrometry-unknown-spike-analysis.md) for fluorinated molecules [Elemental analysis](https://filab.fr/nos-prestations/analyse/analysis-chimiques/laboratoire-analysis-elementaires/) [analysis according to PPWR](https://filab.fr/en/our-services/our-analysis-services/laboratory-material-testing/ppwr-analysis.md) Analysis of APIs, excipients, raw materials, reagents, solvents in the pharmaceutical sector [PFAS analysis on a steel coating](https://filab.fr/en.md) ![pfas](https://filab.fr/wp-content/uploads/2025/02/pfas.gif) ### PFAS: where do we stand with the regulations? Since French law**No. 2025-188 of February 27, 2025** (Environmental Code, Art. L.524-1), the use of products containing PFAS has been progressively banned, **with key deadlines:** - **Since January 1, 2026**: ban on placing certain products containing PFAS on the market (including cosmetic products). - **From 2030**: extension to textiles and other industrial uses (with exemptions for essential uses). - **REACH Regulation (EU)**: a “universal” PFAS restriction is currently being assessed by the ECHA, strengthening control and traceability obligations across supply chains. - **Firefighting foams:** gradual ban in the EU, with a regulatory threshold of 1 mg/L for the sum of PFAS. ***We invite you to contact us to find out the applicable thresholds for your product and to discuss with our experts how they should be interpreted in relation to your matrix 📞📧.*** ## Our analytical capabilities in PFAS expertise [### LC\/MS-MS](https://filab.fr/en/our-technical-resources/altis-lc-msms-analysis.md) [### GC\/MS-MS](https://filab.fr/en/our-technical-resources/gc-msms-analysis-laboratory.md) ### HC-GC\/MS [### CI](https://filab.fr/en/our-technical-resources/laboratory-ion-chromatography.md) [### Py-GCMS](https://filab.fr/en/our-technical-resources/py-gc-ms-pyrolysis-gc-ms.md) ## PFAS analysis: which matrices should you entrust to FILAB? Identifying PFAS compounds requires specific extraction protocols depending on your industry. As a PFAS expert laboratory, FILAB works on a wide variety of complex industrial matrices: - Materials and packaging: testing of polymers, textiles, and food-contact packaging. - Formulations and finished products: regulatory compliance analysis (REACH) for cosmetics or chemical products. Whether you are looking for a responsive PFAS testing lab for routine checks or a PFAS expert lab to develop methods on atypical matrices, our engineers adapt to your needs. Expertise, preuves et traçabilitéMise à jour : juin 2026 ## Trust FILAB laboratory for your analysis of per- and polyfluoroalkyl substances (PFAS) Confier votre analyse de substances per- et polyfluoroalkylées (PFAS) au laboratoire FILAB, c’est s’appuyer sur une expertise technique, un cadre qualité documenté et une lecture experte des résultats pour des décisions industrielles, qualité ou réglementaire. ### Accréditations reconnues - ** ISO 17025 - ** SAFRAN - ** FRAMATOME - ** EDF [Nos accréditations](https://filab.fr/en/about-us/accreditations-en.md) ### Un expert à votre contact - [** Barbara Beauvais](https://www.linkedin.com/in/barbara-beauvais/) Responsable expertise Barbara Beauvais accompagne les projets d’analyse de substances per- et polyfluoroalkylées (PFAS). [Notre équipe](https://filab.fr/en/about-us.md) [Our team](https://filab.fr/en/about-us.md) ### Recognized accreditations - ** ISO 17025 - ** SAFRAN - ** FRAMATOME - ** EDF ### An expert at your side - [** Barbara Beauvais](https://www.linkedin.com/in/barbara-beauvais/) Expertise Manager Barbara Beauvais supports projects for the analysis of per- and polyfluoroalkyl substances (PFAS). [Our team](https://filab.fr/en/about-us.md) Notre démarche en 4 étapes : 1. **Échange** sur votre problématique et vos contraintes. 2. **Proposition** d’un protocole analytique adapté et d’un devis. 3. **Réalisation** des analyses et relecture experte des résultats. 4. **Livraison** d’un rapport détaillé, exploitable et traçable. [Nos moyens techniques](https://filab.fr/en/our-technical-resources.md) [Avis vérifiés](https://www.avis-verifies.com/avis-clients/filab.fr) ## Les avis de nos clients L **Lucile g.** 10 June 2026 "I used Filab for a chemical analysis. Very satisfied with the service. Responsive team, deadlines met, and a clear analysis report. I recommend them." 5/5 N **Nicolas a.** 12 May 2026 "Very responsive laboratory, with excellent analysis quality and deadlines met. Communication is smooth, the technical explanations are clear, and the team knows how to adapt to specific needs. I recommend them for their professionalism and reliability!" 5/5 C **Charlotte t.** 8 May 2026 "Clear and precise deliverable, delivered on time. I recommend them." 5/5 [Voir tous les avis](https://www.avis-verifies.com/avis-clients/filab.fr) Transparence & contactDernière vérification : juin 2026 ## Où nous trouver et comment nous contacter FILAB est un laboratoire physique situé en France, indépendant et accrédité. Toutes les coordonnées ci-dessous permettent de vérifier notre identité et de lancer votre demande. ![](https://filab.fr/wp-content/uploads/2026/06/filab-exterieur.gif) ### Laboratoire FILAB Ecoparc Dijon Bourgogne 80 rue Jean-Louis Auguste Petitjean 21850 Saint-Apollinaire, France Tél. [+33 (0)3 80 52 32 05](tel:+33380523205) ### Resources - [PFAS substances: The invisible challenge for industry](https://filab.fr/blog/2024/01/susbtances-pfas-defi-industrie.md) ## FAQ What is a PFAS analysis in the laboratory? A PFAS analysis aims to detect and quantify per- and polyfluoroalkyl substances present in a matrix (liquid, solid, powder, polymer, etc.) using chromatography techniques coupled with mass spectrometry (LC-MS/MS). Where are PFAS found? These substances are used for their non-stick, water-repellent, and heat-resistant properties in: - **non-stick coatings** (cookware, technical textiles); - **cosmetics and food packaging** ; - **industrial additives** (paints, varnishes, lubricants). **What types of samples can be tested for PFAS?******The FILAB laboratory analyzes PFAS in **pharmaceutical products**, **cosmetics**, **solvents**, **food packaging**, and **polymer materials**. What techniques are used for PFAS analysis? analysis are carried out mainly by **LC-MS/MS** or by **ionic combustion (CLI)** for total fluorine determination. These methods enable detection at thresholds of 1 to 10 ppb depending on the matrix. Which PFAS are measured by the laboratory? The FILAB laboratory offers the analysis of **36 PFAS**, including the 20 substances mentioned in the European Water Directive, such as PFOA, PFOS, PFHxA, PFNA or PFDA. What regulatory changes concern PFAS? Since February 2025, French law has provided for the gradual ban of PFAS in **cosmetics**, **clothing textiles** and **ski waxes** as of **January 1, 2026**. Why carry out a PFAS analysis? In the event of regulatory non-compliance, a process improvement, or a product [failure](https://filab.fr/en/our-services/our-expertise-services/laboratory-analysis-failures.md), manufacturers may need to carry out analysis of per- and polyfluoroalkyl substances. Subject to significant regulatory constraints, monitoring their presence is therefore essential. Carrying out these substance checks requires precise tools, capable of reaching ppm or even ppb levels. At FILAB, they are carried out by LC-MSMS and we are able to achieve a quantification limit of 1 to 10 ppb depending on the matrices.