---
type: "WebPage"
title: "Analysis of heavy metal residues according to ISO 19227"
description: "Actors of the Medical Devices sector, you wish to analyze the heavy metal residues on your products What is the 19227 standard? The international standard ISO 19227 with the name \"Surgical implants - Cleanliness of orthopaedic implants - General requirements\",..."
resource: "https://filab.fr/en/our-services/our-expertise-services/laboratory-analyis-standard-iso-19227/analysis-of-heavy-metal-residues-according-to-iso-19227/"
tags: ["EN", "pll_62bd499faf109", "Anaïs DECAUX"]
timestamp: "2025-12-31T08:43:29Z"
published: "2022-07-04T14:05:49Z"
language: "en"
author: "bwa"
---

# Analysis of heavy metal residues according to ISO 19227

## Actors of the Medical Devices sector, you wish to analyze the heavy metal residues on your products

### What is the 19227 standard?

The international standard ISO 19227 with the name “**Surgical implants – Cleanliness of orthopaedic implants – General requirements**“, describes the requirements for the cleanliness of orthopaedic implants as well as the validation of the cleaning processes used.

The objective of cleaning validation via [ISO 19227:2018](https://filab.fr/en/our-services/our-expertise-services/laboratory-biocompatibility-testing/laboratory-exhaustiveness-verification-iso-10993-12.md) is to verify the effectiveness of the cleaning process in reducing physical, chemical and microbiological contaminants below a customer-defined level.

### Why analyze heavy metals according to the 19227 standard?

Although some are essential to industry (lead, chromium, etc.), other heavy metals have a particular toxicological profile (mercury, titanium, etc.).

Thus, their use is strongly regulated in the medical devices sector.

Therefore, the analysis of **heavy metals** according to the 19227 standard, allows to check the conformity of your medical devices and to put them on the market.

## FILAB supports you in the analysis of heavy metals according to the 19227 standard

FILAB laboratory offers a wide range of services, some of which are COFRAC ISO 17025 accredited ([www.cofrac.fr](https://www.cofrac.fr/)), according to validated and documented methods, helping you to comply with the requirements of the [ISO 19227](https://filab.fr/en/our-services/our-expertise-services/laboratory-biocompatibility-testing/laboratory-exhaustiveness-verification-iso-10993-12.md) standard.

## To go further

[Analysis of organic contaminations](https://filab.fr/en/our-services/our-expertise-services/laboratory-analyis-standard-iso-19227/laboratory-analysis-measurements-total-organic-carbon-toc.md) by TOC meter, GCMS, LCMS 

Surface analysis by[SEM-FEG](https://filab.fr/en/our-technical-resources/laboratory-analysis-sem-scanning-electron-microscopy/laboratory-analysis-contaminants.md) or [Optical Microscope](https://filab.fr/en/our-technical-resources/laboratory-of-analysis-and-observation-by-optical-microscope-mo.md)

[Training in cleaning process validation](https://filab.fr/en/our-services/rd/life-cycle-of-an-analytical-method-in-the-laboratory/laboratory-analytical-method-validation/)

Search for traces in a cleaning product (detergent, oil, lubricant...) 

Inorganic contamination analysis by [ICP-MS](https://filab.fr/en/our-technical-resources/our-mineral-analysis-equipment.md) and CLI