---
type: "WebPage"
title: "Hot GPC analysis in the laboratory"
description: "Your needs: hot GPC analysis of your materials What is a GPC analysis? Gel Permeation Chromatography (GPC), also known as Steric Exclusion Chromatography (SEC), is a characterisation technique for determining average molecular weights and molar mass distributions. This technique is..."
resource: "https://filab.fr/en/our-technical-resources/hot-gpc-analysis-in-the-laboratory/"
tags: ["EN", "pll_65aa75b28524f", "Chemical analysis"]
timestamp: "2025-12-31T08:33:48Z"
published: "2024-09-04T11:27:11Z"
language: "en"
author: "bwa"
---

# Hot GPC analysis in the laboratory

## Your needs: hot GPC analysis of your materials

### What is a GPC analysis?

[**Gel Permeation Chromatography**](https://en.wikipedia.org/wiki/Gel_permeation_chromatography) (GPC), also known as Steric Exclusion Chromatography (SEC), is a characterisation technique for **determining average molecular weights and molar mass distributions**. This technique is used to separate molecules according to their size and molecular shape. The dissolved sample is injected via a mobile phase (or eluent) through a column with a controlled porosity packing (known as the stationary phase). The FILAB laboratory, expert in GPC analysis, can help you with your problems.

By using this form of size exclusion chromatography and combining a series of detectors (RI and UV concentration, RALS/LALS light scattering, viscometer), the GPC/SEC technique can accurately determine molecular mass and size as well as intrinsic viscosity and structure, particularly of polymers.

### What is hot GPC?

Hot GPC, or High Temperature Gel Permeation Chromatography, is a chromatography method used to analyse thermally stable polymers. It is particularly suitable for analysing polymers that are not soluble at room temperature, such as certain plastics (polyesters, polyethylenes), resins or rubbers.

## Our solutions: FILAB can help you with your hot GPC analysis needs

### Our hot GPC analysis services

From analysis to R&D, the FILAB laboratory offers multi-sector expertise to meet several types of demand related to the hot GPC technique:

[**Control of** average **molecular weights**](https://filab.fr/en/our-services/our-analysis-services/chemical-analysis-laboratory/laboratory-molecular-characterization.md) and molar mass distribution of polymeric materials and other substances (Mn, Mw, Mp, polydispersity index). Standards NF T 51-505 and the ISO 13885 series are particularly relevant to this type of service.

**Structural characterisation**, including the study of the branching of macromolecular chains (branching analysis, etc.)

**Optimisation of**manufacturing **processes**to validate synthesis, application or cross-linking conditions

[**Assessment of failures**](https://filab.fr/en/our-services/our-expertise-services/laboratory-analysis-failures.md)on thermoplastic parts that may be associated with degradation of the polymer fraction (shearing of the material leading to chain breaks)

Polymer [**deformation**](https://filab.fr/en/our-services/our-expertise-services/laboratory-deformulation-analysis-reverse-engineering.md) to provide physico-chemical information to complement analytical techniques such as [FTIR](https://filab.fr/en/our-technical-resources/laboratory-analysis-ftir-spectroscopy.md), [ATG](https://filab.fr/en/our-technical-resources/tga-tga-ftir-and-tga-ms-analysis-at-filab-laboratory.md), [Py-GCMS](https://filab.fr/en/our-technical-resources.md), [GCMS](https://filab.fr/en/our-technical-resources/gas-chromatography-analysis-lab-gc/tdu-gc-ms-analysis/), [LCMS](https://filab.fr/en/our-technical-resources/laboratory-analysis-uplc.md), etc.

**Characterisation of proteins** and **polysaccharides** (sugars).

## our other technical resources for this type of service

[GPC/SEC](https://filab.fr/en/our-technical-resources/laboratory-analysis-gpc-sec.md)

[LC-MSMS](https://filab.fr/en/laboratory-mass-spectrometry-unknown-spike-analysis.md)

[ICP-AES](https://filab.fr/en/our-technical-resources/laboratory-analysis-icp-icp-ms-icp-aes/icp-aes-analysis-laboratory.md) -  [ICP-MS](https://filab.fr/en/our-technical-resources/icp-ms-analysis-laboratory.md)

Py-GCMS

[HPLC](https://filab.fr/en/our-technical-resources/laboratory-analysis-uplc.md)

[CLI](https://filab.fr/en/our-technical-resources/laboratory-ion-chromatography.md)

### Why choose the FILAB laboratory for your hot GPC analyses?

As an independent laboratory with a team of experienced doctors and engineers, FILAB guarantees the **reliability of its results**, **rapid response to requests** and **personalised support** for its customers.