--- type: "WebPage" title: "Peptide sequencing laboratory" description: "Your need: analyse and understand peptide sequences to optimise your biopharmaceutical processes In the development of biopharmaceutical products, understanding the peptide sequence is essential to guarantee product quality and treatment efficacy. Our expertise meets your most exacting requirements, integrating tailor-made..." resource: "https://filab.fr/en/sectors-of-activity/biopharmaceutical/peptide-sequencing/" tags: ["EN", "pll_67b58cde5cb67", "ASD", "Anaïs DECAUX"] timestamp: "2026-03-25T09:34:29Z" published: "2025-02-19T08:51:11Z" language: "en" author: "Laure Durieux" --- # Peptide sequencing laboratory ## Your need: analyse and understand peptide sequences to optimise your biopharmaceutical processes In the development of [biopharmaceutical products](https://filab.fr/en/sectors-of-activity/biopharmaceutical.md), understanding the peptide sequence is essential to guarantee product quality and treatment efficacy. Our expertise meets your most exacting requirements, integrating tailor-made solutions. ### What is peptide sequencing? Peptide sequencing is an essential step in the analysis of peptides and complex biomolecules. It enables the exact order of [amino acids](https://filab.fr/en/our-services/our-analysis-services/chemical-analysis-laboratory/analysis-amino-acids.md) within a [peptide](https://filab.fr/en/sectors-of-activity/biopharmaceutical/biotherapeutic-recombinant-protein-characterization/peptide-analysis-laboratory-by-lc-ms.md) chain to be determined, providing key information for pharmaceutical research, biotechnology and the food industry. ### Peptide sequencing stages From the precise determination of the sequence to the study of specific modifications, each phase offers information to better understand and exploit peptides in your processes. - **Sequence determination**: identify the precise amino acid sequence of a peptide using advanced techniques such as Mass Spectrometry (MS/MS). - **Analysis and encoding**: obtaining and encoding the sequence for functional studies or peptide production. - **Cleavage and modification**: studying signal sequences or specific regions to identify critical modifications or active sites. ## FILAB carries out analysis to detect, quantify and characterise your peptides using cutting-edge technologies ### Expertise in biopharmaceutical matrices Our expertise in peptide sequencing covers a wide range of matrices: - Serums and formulated solutions: to guarantee the quality of [monoclonal antibodies](https://filab.fr/en/sectors-of-activity/biopharmaceutical/biotherapeutic-recombinant-protein-characterization/analysis-characterization-monoclonal-antibodies-mabs.md) and [biomedicines](https://filab.fr/en/our-services/our-analysis-services/laboratory-analysis-nitrosamines/laboratory-analysis-biomedicine.md). - Cell culture media: analysis of peptides from expression systems such as CHO cells. - Complex extracts: sequencing in plant matrices. Using [cutting-edge technologies](https://filab.fr/en/our-technical-resources.md), we offer precise analyses tailored to your industrial needs. ### Peptide sequencing methods Peptide sequencing uses advanced techniques: [Mass spectrometry (MS/MS)](https://filab.fr/en/our-technical-resources/laboratory-analysis-mass-spectrometry.md) to identify amino acids and their modifications High-resolution mass spectrometers, coupled with [HPLC](https://filab.fr/en/our-technical-resources/laboratory-analysis-uplc.md) systems Enzymatic cleavage to fragment peptides before analysis These methods meet the quality and reliability requirements of the biopharmaceutical industry. ## Our services MS/MS mass spectrometry sequencingenables the complete sequence of peptides to be determined and post-translational modifications to be identified. Sequence analysis and encodingSequence analysis and encoding: obtaining and encoding sequences for specific biopharmaceutical or biotechnological applications. Sequence comparison and alignmentComparing sequences to identify mutations or confirm similarities between peptides. ## Our other services for peptides [Peptide analysis by lc-ms](https://filab.fr/en/sectors-of-activity/biopharmaceutical/biotherapeutic-recombinant-protein-characterization/peptide-analysis-laboratory-by-lc-ms.md) [Peptide aggregation analysis](https://filab.fr/en/sectors-of-activity/biopharmaceutical/peptide-aggregation-analysis-laboratory.md) Protein analysis using the following methods: [BCA method](https://filab.fr/en/sectors-of-activity/biopharmaceutical/protein-analysis-bca-method.md), [Lowry method](https://filab.fr/en/sectors-of-activity/biopharmaceutical/protein-analysis-lowry-method.md), [CBQCA method](https://filab.fr/en/sectors-of-activity/biopharmaceutical/protein-analysis-cbqca-method.md), [Bradford method](https://filab.fr/en/sectors-of-activity/biopharmaceutical/protein-analysis-bradford-method.md) [Peptide analysis and characterization](https://filab.fr/en/sectors-of-activity/biopharmaceutical/biotherapeutic-recombinant-protein-characterization/peptide-analysis-biopharmaceutical-services.md) [De novo sequencing](https://filab.fr/en/sectors-of-activity/biopharmaceutical/biotherapeutic-recombinant-protein-characterization/de-novo-protein-sequencing.md) by [HPLC-MS/MS](https://filab.fr/en/our-technical-resources/laboratory-analysis-uplc/laboratory-analysis-hplc-lcms.md) ## Our FAQ Why carry out peptide sequencing? This method provides an in-depth understanding of peptide structure and function, enabling the development of innovative and reliable therapeutic solutions. Here are the main reasons for carrying out peptide sequencing: **Precise characterization**: to determine the sequence and structural properties of a peptide. - **Quality control**: compare sequences to detect variations, impurities or contamination. - **Biomedicine development**: optimising therapeutic peptides by analysing critical sequences. - **Fundamental research**: understanding the evolution and interactions of peptides in different biological contexts. ![](https://filab.fr/wp-content/uploads/2024/08/shutterstock_2413463979-acide-amine-peptide.jpg)