Chemical analysis in a laboratory using Mass Spectrometry (MS)
Your needs: determine the chemical composition of a substance
What is mass spectrometry analysis?
Mass spectrometry analysis is a powerful technique used to identify chemical compounds and determine their molecular structure by measuring the mass-to-charge ratio (m/z) of their ions.
By ionizing the samples to be analyzed, mass spectrometry separates and detects these ions according to their specific mass and charge, enabling accurate identification and quantification of the molecules present, even at very low concentrations.
Why perform mass spectrometry analysis?
Conducting a mass spectrometry analysis in the laboratory is essential for advancing your understanding of materials and substances.
This technique, renowned for its high precision and sensitivity, makes it possible to identify and quantify chemical compounds with great accuracy, even when they are present at extremely low trace levels.
It is used to ensure the purity of analyzed substances, identify complex molecular structures, and detect contamination. Mass spectrometry analysis therefore plays a key role in quality control and research and development, making a significant contribution to innovation, safety, and regulatory compliance across various sectors.
Our solutions: combining mass spectrometry with other analytical tools to provide reliable and accurate results
Why choose FILAB?
For over 30 years, FILAB laboratory has had the experience and specialized analytical equipment required to meet the need for chemical analysis (structure and composition) by mass spectrometry on your pharmaceutical products, chemical substances, or materials. Through tailored support, FILAB laboratory analyzes your industrial issues related to analysis and advises you through to the interpretation of the results.
Mass spectrometry analysis: a cutting-edge technical solution
FILAB relies on a varied and complementary range of analytical equipment to offer you a wide range of analysis, regardless of the type of matrices to be studied. To provide enhanced detection quality, the mass spectrometer is often coupled with:
- Gas Chromatography analysis (GC-MS)
- HPLC-MS or LPC-MS analysis with dual MS detection (LC-MSMS)
- Analysis by ICP-MS
- HR-MS analysis
Our MS analysis services
These analytical techniques enable us to provide the following services:
- Determine the molecular mass of an organic compound
- Analyze unknown peaks by LC-MSMS and GC-MS
- Investigate an impurity responsible for a defect
- Check the compliance of a raw material or finished product
- Detect traces of heavy metals
- Develop analytical methods specific to your products and including mass spectrometry
- Chiral analysis
With dual expertise in chemistry and materials, FILAB supports you with your analysis and expert assessment needs.
4 applications of spectrometric analysis
Purity control of pharmaceutical products : In the pharmaceutical industry, mass spectrometry is used to verify the purity of medicines by detecting and quantifying impurities and synthesis by-products, including powder purity. This analysis is essential for ensuring the safety and efficacy of products before they are placed on the market.
Characterization of active pharmaceutical ingredients (APIs) : Spectrometric analysis enables the precise characterization of the molecular structure of active pharmaceutical ingredients. This includes identifying molecular mass, isotopes, and molecular fragments, which is essential for validating the composition and stability of active substances in medicines.
Analysis of polymers and plastics : In the materials industry, mass spectrometry is used to characterize polymers and plastics, identifying additives, stabilizers, and degradation products. This helps manufacturers optimize material properties and address issues related to durability or performance.
Identification of volatile organic compounds (VOCs) in the environment : Mass spectrometry is used to identify and quantify VOCs in air, water, and soil. This application is particularly important for assessing the impact of industrial activities on the environment.
Our FAQ
Mass spectrometry (MS) analysis can be applied to a wide range of samples:
>Pharmaceutical products: including drugs and their metabolites. Mass spectrometry helps verify their purity, identify active ingredients, and study their metabolism.
>Environmental samples: such as water, air, and soil, for the detection of pollutants, including pesticides, herbicides, and volatile organic compounds (VOCs).
>Chemical substances: organic and inorganic compounds, including polymers, for a detailed analysis of their chemical structure.
>Materials: such as metals, alloys, and semiconductors, to study their composition and properties.
Combining mass spectrometry analysis with other analytical equipment is common practice.
For example, coupling mass spectrometry with liquid chromatography (LC-MS) or gas chromatography (GC-MS) improves compound separation, increasing the accuracy of substance identification and quantification in complex samples.
Integration with tandem mass spectrometry (MS/MS) provides increased specificity and sensitivity for analyzing molecular structures and detecting low-abundance compounds.
At FILAB, we use this synergy between different analytical techniques to address your analytical challenges across various industries, ensuring the excellence and reliability of analytical results.
Working with a mass spectrometry laboratory, such as FILAB, gives industrial companies access to cutting-edge technologies for the precise and reliable analysis of the chemical composition of their materials. Whether for quality control, contaminant identification, or the characterization of new compounds, mass spectrometry offers unmatched sensitivity and specificity. A mass spectrometry testing laboratory can detect traces of elements at very low levels, which is essential for ensuring compliance with standards and optimizing production processes. By choosing FILAB, you benefit from technical expertise and customized solutions to meet your industrial challenges.
A mass spectrometry testing laboratory, such as FILAB, is capable of analyzing a wide variety of industrial samples, from raw materials to finished products, including residues and impurities. Whether polymers, metals, pharmaceutical products, or environmental samples are involved, mass spectrometry provides detailed information on the molecular composition of materials. FILAB's mass spectrometry laboratory is equipped to process complex samples and meet the specific requirements of various industrial sectors, thereby ensuring precise analyses tailored to your needs.
