Heavy metals analysis laboratory

Chemical analysis R&D support Immediate handling of your samples
More than 140 people
More than 140 people at your service
5200 m² laboratory
5200 m² laboratory + 99% of services are provided in-house
Accredited laboratory
Accredited laboratory COFRAC ISO 17025

Your needs: ensure your products comply with heavy metals regulations, in accordance with current standards

What is a heavy metals analysis?

Heavy metals analysis is a laboratory technique used to determine the amount of metals present in a sample.

This analysis is of crucial importance in many industrial sectors, especially cosmetics.

Heavy metals analysis makes it possible to detect the levels of these substances in a given sample, helping ensure compliance with regulations.

The heavy metals to monitor in your substances

testing

Heavy metals analysis

Heavy metals are chemical elements with a density greater than 5 g/cm3. The list of metals considered heavy metals includes:

Our solutions: monitor and analyze the presence of heavy metals with competitive pricing and lead times

Analytical objectives of heavy metals analysis

Heavy metal analysis makes it possible to characterize the presence of trace metallic elements in a matrix and meet different analytical objectives:

  • Identify and quantify the heavy metals present in a material or product
  • Detect metallic contaminationin a raw material or finished product
  • Check the purity and elemental composition of a matrix
  • Verify a product’s compliance with specifications or regulatory requirements

Investigate the origin of contamination or a material defect in an industrial process

Our technical resources dedicated to the analysis and quantification of heavy metals

The FILAB laboratory puts its expertise and state-of-the-art analytical equipment at your disposal for metal analysis, including heavy metals analysis (lead, mercury, arsenic, cadmium, nickel, antimony, etc.) on any type of substance or material.

The analytical technique such as ICP-MS (inductively coupled plasma mass spectrometry) is used to accurately measure the concentration and distribution of these metals in a sample, which can enable rapid, targeted action. In addition, heavy metal analysis can also helpidentify sources of contamination that may be linked to industrial, agricultural, or other activities.

FILAB ISO 17025 accreditations

The COFRAC ISO 17025 accreditation is a recognition for laboratories in the field of analysis.

It certifies the competence to carry out precise tests and calibrations to quantify the presence and concentration of substances, including heavy metals in samples. FILAB’s COFRAC ISO 17025 accreditation is a guarantee of trust for industries.

Since October 2015, the FILAB laboratory has been COFRAC ISO 17025 accredited for:

  • The determination of metallic impurities in raw materials and pharmaceutical products according to the methods recommended by the European Pharmacopoeia 2.4.20 and the United States Pharmacopeia USP 233
  • The determination of heavy metals in finished cosmetic products

To support you in the best possible conditions, the FILAB laboratory is approved for theResearch Tax Credit (CIR).

Heavy metal expertise in the laboratory

Heavy metal expertise at FILAB relies on reference techniques such as ICP-MS, ICP-AES/OES and mercury analysis by amalgamator, combined with suitable sample preparation.

These methods make it possible to accurately quantify metallic elements in pharmaceutical, cosmetic, medical device or industrial material matrices, assess their regulatory compliance and develop or validate robust analytical methods in line with applicable requirements (ICH Q3D, USP 233, ISO 10993-18, CSAR).

Services tailored to each sector:

Pharmaceutical industry

  • Analysis of elemental impurities by ICP according to USP 233 in pharmaceutical products (regulatory compliance with ICH Q3D)
  • Analytical development and validation by ICP MS or AES
  • Determination of heavy metals in chemical matrices used in production (raw materials, intermediates...)

Medical devices

  • Heavy metal analysis in Medical Devices (ISO 10993-18 context)
  • Analytical development and validation by ICP-MS or ICP-AES applied to materials and components

Cosmetics

  • Heavy metal analysis in cosmetic raw materials by ICP-MS: natural mica, sericites, metal oxides (TiO₂, ZnO, iron oxides...), talc, clay
  • Quantitative analysis of heavy metals in finished cosmetic products by ICP-MS : lipstick, eyeshadow, mascaras, eyeliners...
  • Determination of heavy metals to meet CSAR requirements
  • Analytical development and validation by ICP MS or AES for formulations and raw materials

Chemical industry and materials

  • Heavy metal testing: ICP-MS analysis or ICP-AES in chemical matrices: treatment baths, materials, raw materials…
  • Mercury analysis by amalgamator
  • Heavy metal testing in packaging and packaging materials
  • Analytical development and validation by ICP-MS or ICP-AES for material control

Regulations and heavy metal analysis

Heavy metal analysis is necessary to monitor the presence of trace metallic elements in raw materials and products, and thus verify their compliance with regulatory requirements according to industrial sectors.

As legal obligations can vary from one country to another in Europe, it is therefore essential to refer to the specific regulations of each country to know the exact legal obligations regarding heavy metal analysis in industry.

The various regulatory requirements for heavy metals

To learn more about the legal requirements for heavy metal analysis in industry, you can refer to the following regulations:

As legal obligations can vary from one country to another in Europe, it is therefore essential to refer to the specific regulations of each country to know the exact legal obligations regarding heavy metal analysis in industry.

Need help? Filab supports you in better understanding your needs and advises you on the heavy metal analysis required for your activity.

European union general regulation (EC) no. 1881/2006

European Union General Regulation (EC) No. 1881/2006: This regulation sets the regulatory limits applicable to heavy metals in foodstuffs, including lead, cadmium and mercury.

Directive no. 86/278/eec

This directive concerns environmental protection, particularly soils, when sewage sludge is used in agriculture. It establishes detection limits for each metal to ensure soil quality.

European REACH directive

The European Reach Directive (Registration, Evaluation, Authorization and Restriction of Chemicals) aims to improve the protection of human health and the environment by regulating the manufacture, import and use of chemical substances, including heavy metals.

RoHS Directive

The RoHS Directive (Restriction of Hazardous Substances) restricts the use of certain hazardous substances, including some heavy metals such as lead, mercury, cadmium and hexavalent chromium, in electrical and electronic equipment sold on the European market.

ISO 21392

At the FILAB laboratory, heavy metal testing in cosmetic matrices is carried out in accordance with ISO 21392, dedicated to the determination of trace metallic elements in cosmetic products. This approach enables reliable quantification of metals at trace levels.

CSAR

This regulation, which came into force on January 1st, 2021, is the basic regulation for cosmetic products in China.

FAQ

How is heavy metal testing carried out?

To carry out heavy metal testing in a product, an analytical laboratory can use different techniques.

  • The most commonly used technique is atomic absorption spectrometry (AAS). This method involves vaporizing the product to be analyzed to create a cloud of atoms, which are then excited by a light source. The heavy metals present in the cloud absorb part of this light, making it possible to measure their concentration.
  • Another method often used is X-ray fluorescence spectrometry (XRF). This technique uses an X-ray source to excite the heavy metals present in the product. These then emit fluorescence, which makes it possible to measure their concentration.
  • There are also other methods such as ion chromatography, mass spectrometry and voltammetry, which can be used depending on the type of product to be analyzed and the sensitivity required for heavy metal detection.

In all cases, it is important to follow strict protocols to ensure accurate and reliable results. Analytical laboratories must comply with strict quality standards and use state-of-the-art equipment to carry out these important analysis.

How can companies prevent heavy metal contamination in their manufacturing processes?

There are several measures companies can take to prevent heavy metal contamination in their manufacturing processes. Here are a few examples:

  • Identify potential sources of contamination: Companies should carry out a thorough assessment of their manufacturing processes to identify potential sources of heavy metal contamination. This may include the use of raw materials containing heavy metals, inadequate processing or handling equipment, or discharges of contaminated industrial wastewater.
  • Put quality control procedures in place: Companies should implement quality control procedures to ensure that finished products do not contain excessive amounts of heavy metals. This may include regular heavy metal testing and compliance verification protocols, as well as the introduction of strict production standards.
  • Use safer substitutes: In some cases, companies may be able to use safer substitutes to replace heavy metals in their manufacturing processes. More environmentally friendly and sustainable alternatives can be used to replace products containing heavy metals.
  • Train employees: Companies should raise awareness among and train their employees on the risks associated with heavy metal contamination and the preventive measures that must be put in place to minimize risks. Employees should be informed about safety procedures, personal protective equipment, and emergency protocols.
Applications of heavy metal analysis

Heavy metal analysis is used to monitor pollution levels in water and soil, identify sources of pollution, and characterize the behavior of metals under certain conditions. It applies to a range of industries, starting with the luxury goods and jewelry industry, cosmetics, and plastics manufacturing, among others.

Which techniques can detect heavy metals at very low concentrations?

ICP-MS and ICP-AES are the most widely used techniques for quantifying heavy metals at trace or ultra-trace levels. ICP-MS achieves very low detection limits, meeting the requirements of the pharmaceutical, cosmetic, medical device and materials chemistry sectors.

Why is heavy metal analysis essential in the pharmaceutical industry?

It makes it possible to verify compliance with ICH Q3D and USP 233 pharmacopeia by controlling elemental impurities that could affect product safety. Manufacturers must document the levels of arsenic, cadmium, lead, mercury and other residual elements.

How do you assess heavy metals in medical devices?

The analysis is based on extractions simulating use conditions, followed by quantification of metallic elements according to the guidelines of ISO 10993-18, in order to assess the potential for leaching or release.

What checks are required for cosmetic raw materials?

Mineral materials such as mica, sericite, metal oxides, talc, or clay must be analyzed by ICP-MS to ensure the absence of heavy metals that could migrate into finished products.

How can you verify the compliance of finished cosmetic products?

Lipsticks, eyeshadows, mascaras, or eyeliners are analyzed to measure heavy metal content, particularly to meet regulatory expectations and international requirements such as CSAR.

What is the value of ICP for the chemical and materials industry?

ICP technology makes it possible to characterize matrices such as industrial baths, alloys, or raw materials in order to control their elemental composition, detect metallic contaminants, and verify formulation compliance.

Can heavy metal analysis be applied to packaging?

Yes, packaging materials (plastics, polymers, inks, films) can be analyzed to verify the absence of metals that could migrate into pharmaceutical or cosmetic products.

Why use a heavy metals laboratory to analyze a material or product?

Using a heavy metals laboratory makes it possible to identify and quantify trace metallic elements (Pb, Cd, As, Hg) in different samples. Sensitive techniques such as ICP-MS or ICP-OES make it possible to detect these metals at trace levels, identify contamination, and verify the compliance of a material or product.

What analytical techniques does a heavy metals laboratory use to identify and quantify trace elements?

FILAB, a heavy metals laboratory, mainly uses sensitive elemental analysis techniques such as ICP-MS and ICP-OES. After sample preparation, these methods make it possible to detect and quantify many metals simultaneously at trace levels in order to identify contamination and verify the compliance of a material or product.

Why carry out a heavy metal screening for industries?

The search for heavy metals makes it possible to identify and quantify trace elements (Pb, Cd, Hg, As, etc.) in raw materials or products. Performed by ICP-MS or ICP-OES, this analysis makes it possible to detect metallic contamination and verify the compliance of a material or product.

Why carry out precious metal analysis on dogs?

Chons, residues from metallurgical or recycling processes, may contain precious metals such as gold, silver, platinum, or palladium. Their analysis makes it possible to determine the exact content of these elements in order to assess the value of the batch, guide recovery operations, and optimize valorization processes.

Which analytical technique allows the precise measurement of heavy metal concentration in a sample?

Analytical techniques such as ICP-MS (inductively coupled plasma mass spectrometry) are used to accurately measure the concentration and distribution of these metals in a sample, which can enable rapid and targeted interventions.

How can i get a quote for heavy metal analysis?

To obtain a quote, you can contact the FILAB laboratory team via the contact form, by phone, or by email. Simply send us your requirements (type of material, desired analysis, any applicable standard, urgency, number of samples, etc.). A personalized technical and pricing proposal will then be sent to you within 24 to 48 hours.

How long does it take to get a quote for heavy metal analysis?

The FILAB laboratory generally provides a quote for a heavy metals analysis within 24 to 48 hours after receiving your request and the necessary technical information.

The filab advantages
A highly qualified team
A highly qualified team
Responsiveness in responding to and processing requests
Responsiveness in responding to and processing requests
A COFRAC ISO 17025 accredited laboratory
A COFRAC ISO 17025 accredited laboratory
(Staves available on www.cofrac.com - Accreditation number: 1-1793)
A complete analytical facility of 5,200m²
A complete analytical facility of 5,200m²
Tailor-made support
Tailor-made support
Video debriefing available with the expert
Video debriefing available with the expert
Clément BOENARD Head of Inorganic Chemistry Department
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