Disulfide bridge analysis laboratory

Analysis services for biopharmaceuticals Immediate handling of your samples
More than 120 people
More than 120 people at your service
5200 m² laboratory
5200 m² laboratory + 99% of services are provided in-house
Accredited laboratory
Accredited laboratory COFRAC ISO 17025

As a biopharmaceutical manufacturer, you would like to carry out an analysis of disulfide bridges

What is a disulfide bridge?

A disulfide bridge is a covalent bond formed between two sulfur atoms belonging to cysteine residues within a protein or peptide. These bonds are essential to the three-dimensional stability of biomolecules, influencing their structure, biological activity and resistance to environmental conditions. Alterations to disulphide bridges can compromise the efficacy and safety of a product, particularly in the biopharmaceutical and biotechnology sectors.

Why analyse the disulfide bridges?

Disulphide bridges play a key role in the stability and function of proteins and peptides. Their analysis is essential for :

Check the structure and conformation of biomolecules
Ensuring protein stability under real-life conditions
Preventing aggregation and degradation
Meeting the regulatory requirements of the pharmaceutical industry

FILAB supports biopharmaceutical companies in the analysis of disulphide bridges

Why choose FILAB for disulfide bridge analysis?

FILAB, a laboratory of analytical expertise, offers comprehensive services for disulphide bridge analysis. We offer a range of customised methods to assess the properties of proteins and peptides, tailored to the specific needs of each customer.

Our disulfide bridge analysis services

Mapping disulfide bridges in recombinant proteins

Study of the stability of disulphide bridges under oxidative stress

Verification of the stability of disulfide bridges in a peptide

Quantification of disulfide bridges in monoclonal antibodies (mAbs)

Detection of anomalies in the formation of disulfide bridges

Comparative study of formulations to guarantee the integrity of disulfide bridges

Our technical resources

protéines-enzyme-anticoprs
The filab advantages
A highly qualified team
A highly qualified team
Responsiveness in responding to and processing requests
Responsiveness in responding to and processing requests
A COFRAC ISO 17025 accredited laboratory
A COFRAC ISO 17025 accredited laboratory
(Staves available on www.cofrac.com - Accreditation number: 1-1793)
A complete analytical park of 5,200m²
A complete analytical park of 5,200m²
Tailor-made support
Tailor-made support
Anaïs DECAUX Customer Support Manager
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