Analysis of organic additives: Irganox 1010 (CAS No. 6683-19-8), Irganox 1076 (CAS No. 2082-79-3), Irganox 3114 (CAS No. 27676-62-6)

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You wish to carry out an analysis of organic additives from the Irganox family

Analyzing these antioxidants is essential to ensure the performance and durability of polymer materials.

In what context should an analysis of organic additives be performed: Irganox 1010 (CAS No. 6683-19-8), Irganox 1076 (CAS No. 2082-79-3), Irganox 3114 (CAS No. 27676-62-6)

These compounds, belonging to the family of sterically hindered phenolic antioxidants, are crucial for protecting polymers against degradation caused by heat, shear, and oxidation. Their analysis allows for the identification, quantification, and control of their concentration within a polymer matrix to ensure:

  • The thermal stability of the polymer during processing (extrusion, molding).
  • The longevity of the finished product by preventing premature aging.
  • Regulatory compliance (particularly for food contact materials or medical devices) by controlling migration limits.
  • The quality and effectiveness of the stabilization system used (often in synergy with secondary antioxidants such as Irgafos 168).

The primary objective is to guarantee the performance of your products in the face of manufacturing and usage constraints.

What are Irganox 1010, Irganox 1076 and Irganox 3114?

These three molecules are primary antioxidants that act by trapping free radicals generated during polymer oxidation.

Irganox 1010 (CAS No 6683-19-8)

Versatile antioxidant with high molecular weight. It offers very good resistance to extraction and is commonly used in polyolefins (PE, PP), elastomers, polyesters and adhesives.

Irganox 1076 (CAS No. 2082-79-3)

A monofunctional phenolic antioxidant characterized by low volatility. It is particularly effective at stabilizing polyolefins, polyamides, and polyurethanes, and is often valued for its long-term efficacy.

Irganox 3114 (CAS No. 27676-62-6)

Tri-functional antioxidant based on triazine, providing highly effective protection against long-term thermal degradation in a wide range of polymers, including polypropylene and polyethylene.

FILAB meets your needs for the analysis of organic additives: Irganox 1010 (CAS No. 6683-19-8), Irganox 1076 (CAS No. 2082-79-3), Irganox 3114 (CAS No. 27676-62-6)

What techniques are used for the analysis of Irganox?

HPLC

To separate and quantify Irganox from the other ingredients in the formula

GC-MS

To identify and quantify Irganox

LC-MSMS

To detect and quantify traces of Irganox or its degradation products

FTIR

For qualitative analysis on samples of pure Irganox or in the raw material

Why choose FILAB for the analysis of organic additives: Irganox 1010 (CAS No. 6683-19-8), Irganox 1076 (CAS No. 2082-79-3), Irganox 3114 (CAS No. 27676-62-6)

For over ten years, the FILAB laboratory has developed extensive expertise in chemical analysis within the cosmetics industry. Our laboratory boasts state-of-the-art analytical equipment and highly skilled personnel to provide services that meet your compliance requirements for the analysis of organic additives, specifically Irganox 1010 (CAS No. 6683-19-8), Irganox 1076 (CAS No. 2082-79-3), Irganox 3114 (CAS No. 27676-62-6).

FAQ

What is the difference between Irganox 1010, 1076 and 3114?

These three Irganox compounds are all primary phenolic antioxidants, but they differ in their molecular structure and performance:

  • 1010: a tetrafunctional molecule offering high resistance to extraction.
  • 1076: a monofunctional molecule, valued for its low volatility and excellent long-term thermal stability.
  • 3114: a trifunctional molecule that often provides better thermal protection compared to monofunctional compounds. The choice depends on the polymer and the processing method.
Does the analysis allow us to determine if the antioxidant has degraded?

Yes. Sensitive techniques such as LC-MS/MS or HPLC allow us to quantify the amount of remaining additive, as well as the presence of its degradation products (oxidized metabolites). A high proportion of degradation products indicates a significant depletion of antioxidant capacity.

Are there specific regulatory limits for Irganox in cosmetics?

In the absence of a direct active ingredient status, these compounds are primarily controlled as impurities or substances originating from packaging. There is no listed limit as there is for a preservative. The laboratory will ensure that the detected concentration is below the toxicological threshold deemed acceptable within the framework of the product safety assessment (P&I).

Are they considered active ingredients or contaminants?

In the final cosmetic product, they are generally considered impurities or contaminants (leachable substances). They are not added for cosmetic purposes (hydration, UV protection, etc.), but their presence must be assessed for toxicological risk as part of the Product Information File (PIF).

The filab advantages
A highly qualified team
A highly qualified team
Responsiveness in responding to and processing requests
Responsiveness in responding to and processing requests
A COFRAC ISO 17025 accredited laboratory
A COFRAC ISO 17025 accredited laboratory
(Staves available on www.cofrac.com - Accreditation number: 1-1793)
A complete analytical park of 5,200m²
A complete analytical park of 5,200m²
Tailor-made support
Tailor-made support
Video debriefing available with the expert
Video debriefing available with the expert
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