Do you want to carry out analysis of materials using cryo-electron microscopy?
What is cryo-electron microscopy?
Cryo-electron microscopy (cryo-EM) is a cutting-edge technique that allows the observation and analysis of samples at the nanoscale, while preserving their native structure. Thanks to the rapid freezing of samples, this method avoids the degradation associated with traditional preparation, thus offering precise and reliable results.
What are cryo-TEM and cryo-SEM?
Cryo-TEM (Transmission Electron Microscopy): This technique enables in-depth analysis of the internal structures of samples. Thanks to the transmission of electrons through ultra-thin sections of frozen samples, cryo-TEM offers exceptional resolution, ideal for studying structural details at the atomic level, such as proteins, biomolecular complexes or nanomaterials.
Cryo-SEM (Scanning Electron Microscopy): Geared towards the observation of surfaces, cryo-SEM makes it possible to study frozen samples in their native state, without desiccation. This technique is particularly useful for analysing fine topographies, complex interfaces and surface interactions.
Why choose cryo-electron microscopy for your analysis?
Cryo-electron microscopy is an ideal solution for demanding industries such as :
- Pharmaceuticals and biotechnology: study of proteins, viral structures and biomolecular interactions.
- Advanced materials: analysis of nanostructures and complex interfaces.
- Medical devices: characterization of surfaces on a submicron scale.
Analysis by cryo-electron microscopy, a technique specific to the FILAB laboratory
Why choose FILAB for Cryo-ME analysis?
At the laboratory, we have state-of-the-art analytical equipment and experts in cryo-electron microscopy at your disposal. We’re with you every step of the way, from assessing your needs to delivering detailed, interpreted reports.
Our services include:
- Custom sample preparation.
- In-depth analysis with high-resolution images.
- Interpretation of results to meet your industrial
Our Cryo-microscopy analysis services
Over more than 30 years, the FILAB laboratory has developed a wide range of skills in materials characterisation. With a view to offering you the best analytical techniques in line with scientific developments, the FILAB laboratory is now able to offer you the cryo-microscopy technique (cryo-ME) for the following analysis:
Micro-morphological studies
Identification of organic micro-contamination
Study of proteins
Characterization of nanomaterials
FAQ
Cryo electron microscopy is used to analyse materials and nanostructures in their native state. By rapidly freezing the samples, this technique preserves their original structure, making it ideal for studying proteins, polymers, gels, emulsions and nanoparticles at the nanometric scale.
Cryo-TEM focuses on the internal structure of ultra-thin frozen samples by transmitting electrons through them, offering atomic-scale resolution. Cryo-SEM, on the other hand, is dedicated to surface observation and allows detailed analysis of topography, interfaces and surface interactions without dehydration.
Unlike conventional electron microscopy, cryo electron microscopy avoids chemical fixation, drying or staining that can alter samples. This results in more accurate and reliable observations, especially for sensitive materials, soft matter and biological samples.
Cryo electron microscopy can be used to analysenanomaterials, polymers, gels, emulsions, nanoparticles, organic contaminants and complex material interfaces.
FILAB combines over 40 years of expertise in materials characterisation with state-of-the-art cryo electron microscopy equipment. The laboratory offers customised sample preparation, high-resolution imaging and fully interpreted analytical reports tailored to industrial challenges.
