HS-GC/MS analysis in the laboratory

Chemical analysis Problem solving R&D support
More than 120 people
More than 120 people at your service
5500 m² laboratory
5500 m² laboratory + 99% of services are provided in-house
Accredited laboratory
Accredited laboratory COFRAC ISO 17025
CIR
CIR Research tax credit

Your needs: analyze your material or product by HS-GC/MS method

What is a HS/GC-MS analysis?

HS/GC-MS (Headspace Gas Chromatography-Mass Spectrometry) analysis is used to identify and quantify volatile and semi-volatile compounds in various samples. providing precise and accurate measurements of volatile organic compounds (VOCs). 

The sample is heated in a sealed vial, releasing volatile compounds into the headspace, which are then injected into a gas chromatograph for separation and analyzed using mass spectrometry. 

This technique requires minimal sample preparation and is ideal for applications in food and beverage testing, pharmaceuticals, environmental monitoring. 

HS/GC-MS Analysis for Volatile Organic Compounds (VOCs)

This method is particularly adapted for the analysis of volatile compounds, such as

  • odorous objects (ex: plants, oils…)
  • from waste water and contaminated soil samples
  • residual solvents in packaging and pharmaceutical products…

Volatile organic compounds (VOCs) are analyzed through HS/GC-MS in various industrial applications. 

Here are ten examples of volatile organic compounds (VOCs):

Benzene: Used in the production of chemicals and plastics.

Ethanol: Used as a solvent in pharmaceuticals and personal care products.

Toluene: Found in paint thinners, adhesives, and coatings.

Formaldehyde: Present in building materials and household products.

Acetone: Used in nail polish removers and as a solvent in the automotive industry.

Xylene: Found in printing, rubber, and leather industries.

Limonene: Used in the perfume and fragrance industry.

Linalool: Commonly found in soaps, shampoos, and detergents.

Methylene Chloride: Used in paint strippers and degreasing agents.

Trichloroethylene: Used in industrial degreasing and dry cleaning processes.

These VOCs are monitored and analyzed in various industries using HS/GC-MS to ensure safety, quality, and regulatory compliance across industries.

Our solutions: provide you with our expertise in HS/GC-MS analysis and support in interpreting the results

For more than 30 years, our laboratory FILAB has had the experience and the specific analytical equipment to assist companies in the HS/GC-MS analysis of their formulas, polymeric or composite materials, through a tailor-made support.

As an independent laboratory, with a team of experienced doctors and engineers, FILAB guarantees the reliability of its results. In addition, FILAB ensures rapid processing of requests as well as personalized support for its clients.

From analysis to R&D, FILAB offers multi-sectoral expertise for several types of services.

Our services with HS GC MS method

examples of services

Analysis by TDU-GC-MS themodesorber

Dosing of substances in food products, cosmetics...

Chemical characterization according to standard 10993-18 (medical devices)

Industrial Applications of HS/GC-MS Analysis

Chemical and Plastics Manufacturing and Benzene

Benzene is a key raw material in the production of various chemicals and plastics. HS/GC-MS analysis is used to monitor benzene levels to ensure process efficiency, product quality, and compliance with safety regulations, given its toxic nature.

Pharmaceutical Industry and Ethanol

Ethanol is used as a solvent and preservative in many pharmaceutical formulations. HS/GC-MS analysis ensures the correct concentration of ethanol in medicinal products, guaranteeing efficacy, safety, and adherence to stringent regulatory standards.

Paints and Adhesives Manufacturing and Toluene

Toluene is used as a solvent in paints, coatings, and adhesives. HS/GC-MS is utilized to monitor and control toluene levels, ensuring compliance with environmental regulations and occupational safety standards, as well as maintaining product performance.

FAQ

What is hs spme gc ms ?

HS-SPME-GC-MS (Headspace Solid-Phase Microextraction Gas Chromatography-Mass Spectrometry) is an advanced technique for detecting and quantifying volatile and semi-volatile compounds. It involves heating a sample to release volatile compounds into the headspace, adsorbing them onto a sorbent-coated fiber. This fiber is then inserted into a gas chromatograph for separation and subsequent identification and quantification using mass spectrometry. Widely used in environmental monitoring, food and beverage testing, forensic science, and pharmaceuticals, HS-SPME-GC-MS offers high sensitivity, minimal sample preparation, and effective analysis of complex mixtures.

What are the differences between hs spme gc ms et hs-gc-ms ?

HS-SPME-GC-MS and HS-GC-MS both analyze volatile compounds but differ in extraction methods. HS-SPME-GC-MS uses a sorbent-coated fiber to adsorb compounds, offering higher sensitivity and lower detection limits. HS-GC-MS directly samples headspace gas, simplifying the process and reducing preparation time, making it suitable for rapid analysis in industrial quality control.

The filab advantages
A highly qualified team
A highly qualified team
Responsiveness in responding to and processing requests
Responsiveness in responding to and processing requests
A COFRAC ISO 17025 accredited laboratory
A COFRAC ISO 17025 accredited laboratory
(Staves available on www.cofrac.com - Accreditation number: 1-1793)
A complete analytical park of 5,500m².
A complete analytical park of 5,500m².
Tailor-made support
Tailor-made support
Thomas ROUSSEAU Scientific and Technical Director
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