Do you need to test your raw material or products for nitrosamines using the Apparent Total Nitrosamine Content (ATNC) method ?
What are nitrosamines?
Nitrosamines are a group of chemical compounds, more specifically nitrous acid amides, formed by the chemical reaction between secondary amines and nitrosating compounds. They are often produced unintentionally during industrial processes and are widely recognized for their carcinogenic potential.
Why test your products or raw material for nitrosamines ?
Combating the formation of nitrosamines is a global strategy, established by regulations and the recommendations of professional bodies.
In fact, nitrosamines have been classified as dangerous substances and potentially carcinogenic to humans by the IARC and the WHO. This is why strict European regulations have been laid down (CE 1223/2009) stating that nitrosamines should not be included in the composition of cosmetic products above trace levels technically unavoidable under good manufacturing practice.
The FILAB laboratory analyzes and doses nitrosamines in your cosmetics using the ATNC method.
What is the ATNC method?
The GC-TEA ATNC method (Gas Chromatography coupled to Thermal Energy Analyzer for Analysis of Apparent Total N-Nitroso Compounds) is an analytical technique specialising in the detection and quantification of apparent total N-nitroso compounds (ATNC). These compounds are potentially carcinogenic substances formed by the nitrosation of amines in the presence of nitrites, particularly in food, pharmaceutical or environmental contexts.
Do you need a laboratory capable to dectect the apparent total nitrosamine content (ATNC)?
In order to support cosmetics manufacturers or others industries in the development and quality control of their products, in line with regulatory developments, the laboratory provides state-of-the-art analytical equipment, enabling the determination of nitrosamines using the ATNC (Apparent Total Nitrosamines Content) method.
Analyses are performed using a variety of methods, such as LC-MSMS, GC-MS, GC-TEA or GC-MS/MS combined with LC-UV.
Why choose FILAB for your ATNC nitrosamine analysis?
To meet these challenges, you need the support of a reliable, independent cosmetics analysis laboratory with high technical added value.
FILAB, a laboratory staffed by experts in cosmetics analysis and failure characterization, offers you analytical services from design to manufacture and marketing of cosmetic products (make-up, creams, perfumes, etc.).
FAQ
Does Filab perform ATNC testing in Europe?
FILAB is an accredited, high-performance ATNC laboratory - ATNC testing / ATNC laboratory - offering its services throughout Europe.
Our ATNC testing services in Europe include :
Total apparent nitrosamines content (ATNC) by GC-TEA: This advanced technique accurately detects and quantifies the total amount of nitrosamines present in a sample.
TEA nitrosamines analysis for the pharmaceutical and cosmetics industries: We guarantee product safety by assessing the absence of ATNC contamination in raw materials, intermediates and finished products, in compliance with current regulations.
Our strengths as an ATNC testing laboratory in Europe:
In-depth scientific and technical expertise: Our team of experienced analysts is at the cutting edge of the latest ATNC testing techniques, guaranteeing accurate and reliable results.
Accredited, state-of-the-art laboratories: Our state-of-the-art facilities meet the most stringent standards for ATNC analysis, ensuring quality and consistency of results.
Rigorous, methodical approach: We apply rigorous procedures and strict quality controls to ensure the validity and reliability of every analysis.
What types of ATNC testing does FILAB offer ?
Our laboratory offers a comprehensive range of ATNC analyses, covering a wide variety of samples. Our experts use state-of-the-art techniques, such as gas chromatography coupled with thermo-analysis detection (GC-TEA) and mass spectrometry (MS), to guarantee accurate, reliable analysis. Filab specializes in the analysis of nitrosamines, potentially carcinogenic organic compounds found in a variety of products, including cosmetics, medicines and foods. We offer analyses of total nitrosamines (ATNC) by GC-TEA, as well as specific analyses of individual nitrosamines, such as N-nitrosodiethanolamine (NDELA) and N-nitrosomethylethanolamine (NMEA).
Is Filab authorized to carry out nitrosamines analysis by ATNC for all types of industry?
Our laboratory has recognized expertise in the field of ATNC and nitrosamine analysis, and we are able to meet the specific needs of all types of industry, including
- Pharmaceutical industry: Analysis of raw materials, intermediates and finished products to guarantee absence of contamination and nitrosamines by ATNC method.
- Cosmetics industry: Analysis of ingredients, formulations and finished products to ensure regulatory compliance and consumer safety.
What types of ATNC testing does Filab offer?
At Filab, we provide a comprehensive suite of ATNC testing services using cutting-edge technologies. Our expert analysts utilize techniques like Gas Chromatography coupled with Thermal Electron Affinity Detection (GC-TEA), Mass Spectrometry (MS), and immunoassays to deliver accurate and reliable results.
Do Filab offer total nitrosamines content analysis?
Yes, Filab is equipped to perform total nitrosamines content analysis using GC-TEA. This method effectively detects and quantifies the total amount of nitrosamines present in a sample. Additionally, we offer analyses for specific nitrosamines like N-nitrosodiethanolamine (NDELA) and N-nitrosomethylethanolamine (NMEA), crucial for the pharmaceutical and cosmetic industries.
Nitrosamine testing by thermal energy analysis (TEA) is a method used to analyze the presence of nitrosamines in various products. Nitrosamines are a group of chemical compounds that may be carcinogenic and found in some foods, cosmetics and pharmaceuticals. The TEA nitrosamines testing method involves heating the sample in question, which causes the nitrosamines present to break down into smaller molecules. These molecules can then be detected and analyzed using specialized equipment such as mass spectrometers.
Can Filab handle nitrosamines testing by ATNC for various industries?
Absolutely! Filab's expertise encompasses ATNC and nitrosamines testing for a wide range of industries, including:
- Pharmaceutical Industry: We analyze raw materials, intermediates, and finished products to guarantee the absence of ATNC and nitrosamines, ensuring patient safety and regulatory compliance.
- Cosmetic Industry: Our services ensure the safety of cosmetic ingredients, formulations, and final products by testing for ATNCs and nitrosamines, adhering to relevant regulations and consumer protection.
- Food and Beverage Industry: We analyze raw materials and packaging to identify potential nitrosamine presence, safeguarding consumer health.
Why choose Filab for nitrosamines testing by ATNC ?
- Unmatched Scientific and Technical Expertise: Our team of highly qualified analysts stays updated on the latest ATNC and nitrosamines testing methodologies.
- State-of-the-Art Equipment and Accredited Laboratories: Our facilities are equipped with advanced instruments, ensuring the accuracy and consistency of our analyses.
- Meticulous and Rigorous Approach: We adhere to strict protocols and quality control measures to guarantee the validity and reliability of every test.
- Comprehensive and Interpreted Reports: You receive detailed reports with clear interpretations, facilitating informed decision-making.
Commitment to Client Satisfaction: We prioritize exceptional customer service, catering to your specific needs and providing support throughout the testing process.
Contact Filab today for your nitrosamines testing needs
Our team is dedicated to providing you with exceptional nitrosamines testing by ATNC services. We can customize a testing plan that aligns with your specific requirements and industry regulations. Let Filab be your partner in ensuring product safety and advancing scientific research in the field of ATNCs and nitrosamines.
