Nuclear Magnetic Resonance Analysis (NMR Testing) in a Laboratory
Would you like to carry out a laboratory NMR testing / NMR analysis?
In the FILAB laboratory, we offer NMR (Nuclear Magnetic Resonance Spectroscopy) analysis to provide accurate, in-depth solutions for different industries. This technique allows us to probe the molecular structure and chemical composition of substances, providing information for research, product development, quality control and much more.
The FILAB laboratory provides analytical and expertise services using NMR
Our NMR analysis equipment and technical capabilities
As part of the development of a new product, a conformity study or following a defect in your product, FILAB offers you a specific NMR analysis service:
- BRUKER 300 MHz
- BRUKER 400 MHz
- BRUKER 500 MHz with CMAS solid probe
- BRUKER 600 MHz with liquid nitrogen cryoprobe / HRMAS
- 60MH low-field NMR apparatus
The NMRs are also equipped with autosamplers. The nuclei considered are generally the following: H, C, F, Si, P, B, Sn, Se, Pt… FILAB offers these analysis with the support of a partner laboratory.
Our Nuclear Magnetic Resonance (NMR) analysis services
Custom NMR chemical analysis of liquids or solids
Interpretations of NMR spectra
Molecule modification
Development of analytical techniques using NMR
Molecular structural analysis of a sample using NMR
What is Nuclear Magnetic Resonance analysis (NMR analysis)?
Nuclear Magnetic Resonance (NMR) is an analytical technique used primarily to determine the structure and composition of molecules, by characterising them.
NMR is extremely effective for determining the structure of organic and inorganic molecules, and identifying functional groups and the arrangement of atoms in a molecule. Thanks to this analysis, the laboratory can identify the molecular structure, chemical bonds and dynamics of molecules.
In addition, NMR is a non-destructive technique, enabling samples to be analysed without altering or destroying them.
Why Perform a Nuclear Magnetic Resonance analysis (NMR analysis) in a Laboratory?
Carrying out NMR (Nuclear Magnetic Resonance) analysis in the laboratory has many advantages, making this technique essential in various fields of research and industry:
- Purity and composition analysis: this is used to analyse the purity of compounds and detect impurities, even in very low concentrations, as part of chemical analysis and product quality control.
- Pharmaceutical development: in the pharmaceutical industry, NMR is essential for the design and validation of drugs, enabling the structure and conformity of active ingredients to be analysed.
- Polymers and materials: it is also used to characterize materials such as polymers, by determining their chemical composition and physical properties.
In short, NMR is a versatile and powerful technique, indispensable in many sectors for its ability to provide complete and accurate information on the chemical structure and properties of molecules.
Our complementary analysis services
FILAB laboratory also offers analytical services complementary to NMR analysis, strengthening the value of the analysis :
- Determination of absolute molecular weight using GC/SEC
- GC-MS analysis
- Liquid chromatography analysis coupled to a mass spectrometer (LC-MS)
- Matrix-assisted desorption/ionization mass spectrometer (MALDI-MS)
- Analytical development and validation for measuring the molecular weight of your samples
The principles of NMR analysis
Nuclear Magnetic Resonance (NMR) analysis is based on three fundamental principles: the magnetic field and nuclear spin, radio frequency excitation and the analysis of NMR signals.
It is based on the principle that certain atomic nuclei, such as hydrogen and carbon, have magnetic properties. When placed in a strong magnetic field and exposed to specific radiofrequency waves, these nuclei absorb and emit energy at characteristic frequencies, enabling them to be identified. NMR is therefore based on the detection and analysis of the signals emitted by these nuclei.
FAQ
Nuclear magnetic resonance (NMR) is an analytical technique used to determine the chemical structure of molecules by observing the interactions of atomic nuclei with a magnetic field. This method is essential for identifying compounds, assessing the purity of a sample and understanding its molecular properties.
An NMR spectrum provides information about the different chemical environments of nuclei in a sample. Analysis of a 1st order NMR spectrum allows molecular structure to be deduced by examining parameters such as NMR chemical shift and coupling constants.
NMR chemical shift measures the change in resonance frequency of a nucleus relative to a standard reference. It reflects the electronic environment of the nucleus and helps to identify the different atoms within a molecule. It is a key element in the analysis of an NMR spectrum.
NMR spectroscopy is the experimental technique used to obtain NMR spectra. The term ‘nuclear magnetic resonance (NMR)’ refers to the underlying physical phenomenon, while NMR spectroscopy refers to the use of this technique to analyse samples.
The Filab laboratory offers NMR analysis for a wide range of samples, including organic compounds, polymers and pharmaceuticals. Using NMR spectroscopy, we can identify molecular structures and assess the purity of submitted samples.
In the Filab laboratory, we use NMR spectroscopy to analyse samples, focusing on the interpretation of NMR spectra, the study of chemical shifts and spin-spin couplings. These analyses provide accurate results on the composition and molecular structure of samples.
In the pharmaceutical sector, it enables the structural elucidation and purity control of active ingredients.
In the chemical and polymer industries, it helps to determine molecular weight distribution, monomer composition, and crosslinking levels.
In materials science, NMR is used to study the structure and dynamics of polymers, composites and additives, providing insight into the physical and chemical behavior of materials.
Overall, NMR is a powerful and versatile analytical tool for understanding the molecular structure, quality, and stability of industrial materials.
Both nuclear magnetic resonance analysis (NMR) and infrared (IR) spectroscopy are techniques used to determine the chemical structure of substances — but they provide different and complementary types of information.
Infrared spectroscopy detects the vibrations of chemical bonds and identifies functional groups within a molecule.
Nuclear magnetic resonance analysis, on the other hand, examines the magnetic environment of atomic nuclei (such as hydrogen or carbon) to reveal the full molecular structure and the arrangement of atoms in space.
In short, IR spectroscopy identifies the types of bonds present, while NMR analysis determines how atoms are connected and organized. Combining both techniques allows for a complete and precise characterization of materials.
