Particle size measurement and particle size distribution of nanomaterials according to OECD 125
OECD 125: determine your particle size according to international standards
Why carry out analysis according to OECD 125?
Performing analysis in accordance with OECD Guideline 125 is essential for a number of reasons :
OECD 125 establishes a precise framework for measuring the size and particle size distribution of particles and fibres in the range 1 to 1000 nm. This characterisation is crucial for :
- Validate the properties of a material in a research and development context.
- Compare different production batches to ensure product consistency and quality.
- Understanding the behaviour of nanomaterials, particularly in terms of reactivity and interactions with the environment.
The use of nanomaterials is subject to strict regulations in various sectors (cosmetics, pharmaceuticals, medical devices, chemicals, etc.). Following the OECD 125 standard allows you to :
- Meet regulatory obligations relating to the classification of nanomaterials (REACH, FDA, ISO, etc.). nanomatériaux (REACH, FDA, ISO, etc.).
- Provide reliable data to the authorities for the registration and marketing authorisation of products containing nanomaterials.
- Demonstrate the safety of a product in relation to current regulations.
The methods recommended by OECD 125 are based on proven techniques (SEM, TEM, DLS, SAXS, etc.) and validated by inter-laboratory studies. This guarantees
- Standardised results, enabling reliable comparisons between laboratories and studies.
- Better traceability of analysis, essential for manufacturers and regulatory bodies.
In sectors such as aeronautics, medical devices and energy, controlling particle size makes it possible to optimise :
- Materials performance (e.g. mechanical, thermal and optical properties).
- Product formulations (e.g. suspension stability, reactivity control).
- Quality control of industrial production, by ensuring that the characteristics of nanoparticles comply with specifications.
The FILAB laboratory assists you in analyzing particle size measurement and the particle size distribution of nanomaterials according to OECD 125
Our other nano services according to the OECD
Why use FILAB?
Mutual Recognition of Data (MAD): In accordance with OECD principles, the data generated by our laboratory is recognized by all OECD member countries. This avoids duplication of testing and facilitates your global exports.
COFRAC ISO 17025 accreditation: a guarantee of scientific rigor, essential for the validity of your dossiers with ECHA.
Nanomaterials expertise: our experts advise you on the most relevant testing strategy for your substance.
Our other nanomaterials expertise services
The FILAB laboratory is ISO 17025 accredited by COFRAC for the characterization of nanomaterials!
our services
Development and validation of nanomaterial-specific analytical methods
Training for your teams (techniques and regulatory issues related to nanomaterials)
Regulatory consulting on nanomaterials (2011 EC Recommendation, EC Cosmetics Regulation n°1223/2009, INCO Regulation n°1169/2011, R-Nano (2012-232, 02/2012)...)
OUR TECHNICAL RESOURCES
SEM-FEG-EDX : counting and determining the size and shape of nanoparticles
Helium pycnometry : density measurement
XRD : structural analysis
DLS : measurement of nano-emulsions and study of suspension stability by Zeta Potential titration.
SP-ICP-MS: detection of nanoparticles
BET : specific surface measurement
Laser granulometry : particle size distribution
ICP-AES and ICP-MS : trace analysis and chemical composition of a nanomaterial-based product
Our FAQ
When it comes to characterizing the particle size and granulometric distribution of nanomaterials, the methodology and precision of the analyses are essential. At the Filab laboratory, we provide our technical expertise and state-of-the-art analytical equipment to guarantee reliable, traceable results that comply with regulatory requirements.
OECD 125 imposes a validation and preparation protocol (choice of solvent, sonication energy) that is much more rigorous than conventional industry standards, guaranteeing the reproducibility of data.
Yes, the standard provides for specific dispersion steps to differentiate primary particles from aggregates and agglomerates, which is essential for regulatory classification.
To obtain a quote, you can contact our team via our contact form, by phone, or by email.
Simply tell us your requirements (type of material, desired analysis, applicable standards, urgency, quantity of samples, etc.). We will then send you a personalized technical and pricing proposal within 24-48 hours.
Turnaround times vary depending on the nature of the analysis and the complexity of the expert assessment project.
However, FILAB is committed to providing fast turnaround times tailored to your industrial constraints and urgent needs.
