Would you like to determine the content of Penicillin G (CAS No. 69-57-8) in your medicines?
Ensuring the compliance and quality of pharmaceutical products
Penicillin is one of the most widely used antibiotics in the world. Precisely determining its content in medicines is a critical issue involving therapeutic efficacy, patient safety, regulatory compliance, and control of manufacturing processes.
At the FILAB laboratory, we support stakeholders in the Pharmaceutical industry with the reliable and reproducible determination of penicillin content, regardless of the product’s development or production stage.
Our analytical services for Penicillin G (CAS No. 69-57-8)
Quantitative determination of penicillin G
Stability studies (monitoring of potency loss)
Assay in complex matrices (injectable forms, powders, formulations)
Batch compliance testing
Identification of degradation products
Our technical resources for the assay of Penicillin G (CAS No. 69-57-8)
GC-MS
LC-MSMS
LC-QTOF
LC-Orbitrap
FILAB laboratory supports pharmaceutical manufacturers with the assay of Penicillin G (CAS No. 69-57-8)
Why assay Penicillin G?
Assaying penicillin G (benzylpenicillin) serves several industrial and regulatory purposes:
Verify the active ingredient content against the specifications in the marketing authorisation application
Check batch compliance during production or batch release
Detect under- or overdosing that could affect efficacy or safety
Investigate a non-conformity or quality deviation
Ensure the drug’s stability over time
In a strict regulatory environment, the reliability of analytical results is critical.
Why choose FILAB for the assay of Penicillin G (CAS No. 69-57-8)
For more than ten years, FILAB laboratory has developed extensive expertise in chemical analysis. Our laboratory has a state-of-the-art analytical equipment fleet and highly skilled personnel to provide services that meet your compliance requirements for the assay of Penicillin G (CAS No. 69-57-8) in your medicines.
FAQ
Penicillin G, also known as benzylpenicillin, is a natural penicillin belonging to the β-lactam family. It is widely used in human and veterinary medicine, particularly in injectable form. Its chemical structure makes it particularly sensitive to hydrolysis, requiring controlled analytical conditions.
Penicillin G assay can be performed on:
raw materials,
finished products (injectable solutions, powders for reconstitution, etc.),
in-process samples,
stability studies.
Each matrix requires suitable sample preparation to ensure reliable results.
This service is intended in particular for:
pharmaceutical laboratories,
contract manufacturers and CDMOs,
veterinary drug manufacturers,
quality, control, production and R&D teams.
Penicillins are a family of β-lactam antibiotics comprising several types of molecules, with different chemical structures, activity spectra and analytical behaviors.
The main groups are:
Natural penicillins :
penicillin G (benzylpenicillin)
penicillin V
They are effective against a relatively narrow spectrum and are chemically sensitive, particularly to hydrolysis of the β-lactam ring.
Semi-synthetic penicillins :
aminopenicillins (amoxicillin, ampicillin),
penicillinase-resistant penicillins (oxacillin, cloxacillin, etc.),
carboxy- and ureidopenicillins (ticarcillin, piperacillin).
Penicillin + β-lactamase inhibitor combinations :
amoxicillin / clavulanic acid,
piperacillin / tazobactam.
