Peptide analysis in laboratory | Peptide mapping - Biopharmaceutical Services
You need to characterize peptides present in your matrices or finished products
Peptides offer great therapeutic potential, but their development presents challenges due to their complexity and varied physicochemical properties. This complexity requires a multitude of analytical techniques to meet strict regulatory requirements.
FILAB’s state-of-the-art analytical facilities and high-level human skills enable us to offer our customers services that meet their compliance criteria for the analysis of peptides in their cosmetics, biopharmaceuticals, etc.
- Characterization and comparative study
- Impurity analysis of raw materials and finished products…
- Analytical method transfer and validation
- Stability studies
FILAB offers peptide characterization and peptide mapping services.
Peptide mapping
This technique ensures that the amino acid sequence of a protein corresponds to the expected sequence.
Modifications occurring after protein translation, such as glycosylations or oxidations, can be identified.
Peptide mapping can be used to check protein integrity and detect unwanted fragments or degradation.
This technique is essential for ensuring the quality of biopharmaceutical products before they reach the market, guaranteeing that the protein structure is correct and compliant with regulatory requirements.
Which industrial sectors use peptides?
Peptides are versatile molecules used in a variety of sectors, from pharmaceuticals to cosmetics… Their specificity and efficacy enable them to play a key role in developing new treatments or improving skin care. This diversity of applications underlines the considerable potential of peptides and the importance of continuing research in this field.
our technical resources
Mass spectrometry (MS)
Mass-coupled Gas Chromatography (GC/MS)
Liquid chromatography HPLC-MS and HPLC-MS/MS (Orbitrap)
MALDI-TOF
LC-QTOF-MS
FAQ
What is a peptide?
A peptide is a polymer of amino acids linked together by peptide bonds. There is a wide variety of peptides. A peptide can be considered a small protein, or rather, a segment of a protein, as proteins are made up of one or more long chains of peptides. The main distinction between a peptide and a protein lies in their size. FILAB carries out peptide analyses.
Why analyze peptides?
L'analyse des peptides est essentielle pour plusieurs raisons :
- Identification et quantification dans des échantillons complexes.
- Détermination de la séquence des acides aminés.
- Études des modifications post-traductionnelles.
- Contrôle de la qualité des produits pharmaceutiques et cosmétiques.
What are the advantages of having my peptides analyzed by FILAB?
When you choose FILAB, you benefit from :
- Recognized expertise in chemical and biological analysis.
- State-of-the-art techniques for accurate, reliable results.
- Expert interpretation of results for solutions tailored to your needs.
What is peptide mapping?
Peptide mapping is an analytical technique used primarily for protein characterization, particularly in biopharmaceutical product development. The method involves fragmenting a protein into several smaller peptides via enzymatic digestion. Once fragmented, these peptides are separated and analyzed using techniques such as liquid chromatography-mass spectrometry (LC-MS).
