Laboratory analysis for determining nitrosamine contents

Chemical analysis Problem solving Support R&D
More than 140 people
More than 140 people at your service
5200 m² laboratory
5200 m² laboratory + 99% of services are provided in-house
Accredited laboratory
Accredited laboratory COFRAC ISO 17025

What are Nitrosamines?

Nitrosamines belong to a group of nitrogenous and oxidized chemical compounds. They are the result of a combination of nitrites or nitrates with meat proteins. Whether or not they are meant to be present, nitrosamines can be found in a wide variety of industrial substances, mainly in food production (used as additives), in plastics engineering, in cometic products and even in some medications (solvents). These are a few examples of nitrosamines:

FILAB, an analytical laboratory capable of determining the nitrosamine contents of industrial products

Our laboratory provides industrial manufacturers with a cutting-edge analytical fleet for determining the nitrosamine and nitrosamine precursor contents in any matrix (food, pharmaceuticals, cosmetics, polymers, water…) to help these manufacturers with the development and quality control of their products in accordance with changing regulations.

Analytical Techniques we use:

Gas Chromatography coupled with Mass Spectrometry (GCMS)

Headspace Gas Chromatography coupled with Mass Spectrometry (HS-GC-MS)

Liquid Chromatography coupled with Tandem Mass Spectrometry (LC-MS/MS)

Gas Chromatography coupled with Tandem Mass Spectrometry (GC-MS/MS)

Limits of quantification for the determination of nitrosamines vary from 0,2mg/L to 0,5mg/L depending on the technique used and the type of matrix.

FILAB uses a method validated by COFARC for determining certain nitrosamine contents using LC-MSMS in accordance with the ISO 10993-18 standard

Our Analytical Techniques - nitrosamines testing

LC-MS/MS

LC-QTOF

GC-MS

LC-CAD

LC-UV

Substances classified as being dangerous

Nitrosamines were classified as dangerous and potentially carcinogenic substances by the IARC and the WHO.

They are also monitored by the ANSM (French National Agency for Medicines and Health Products Safety), which is currently conducting more in-depth studies on the risks associated with the presence of nitrosamines in medicines.

The Food and Drug Administration (FDA) monitors and regulates the presence of nitrosamines by establishing safety limits and providing analytical methods to ensure compliance of pharmaceutical products.

The filab advantages
A highly qualified team
A highly qualified team
Responsiveness in responding to and processing requests
Responsiveness in responding to and processing requests
A COFRAC ISO 17025 accredited laboratory
A COFRAC ISO 17025 accredited laboratory
(Staves available on www.cofrac.com - Accreditation number: 1-1793)
A complete analytical park of 5,200m²
A complete analytical park of 5,200m²
Tailor-made support
Tailor-made support
Anaïs DECAUX Customer Support Manager
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