Laboratory analysis of antioxidant additives

Chemical analysis Problem solving R&D support
More than 140 people
More than 140 people at your service
5200 m² laboratory
5200 m² laboratory + 99% of services are provided in-house

The oxidation of cosmetic active ingredients impacts the stability, efficacy, and compliance of formulas.

FILAB supports you with antioxidant analysis to characterize the antioxidant capacity of your cosmetic products and optimize their performance against oxidative stress.

Are you looking for a laboratory offering its expertise to ensure antioxidant analysis in your formulas and finished products?

Analysis of antioxidants: cosmetics, pharmaceuticals and plastics

Antioxidant analysis are used in cosmetics (formula stability, anti-free radical protection), pharmaceuticals (extending the shelf life of active ingredients), and plastics (preventing material degradation).

In the cosmetics sector, they play a role in preserving the integrity of active ingredients (oils, plant extracts, vitamins) and ensuring the durability of formulas against environmental stress.

Antioxidant analysis on cosmetic formulations

Antioxidant analysis measures a cosmetic formula's ability to neutralize free radicals and resist oxidation, ensuring its stability and effectiveness. FILAB conducts these tests to validate your active ingredients and optimize the durability of your products.

  • Chemical tests, such as DPPH, ABTS, FRAP, and ORAC, measure the reduction of free radicals or specific oxidizing agents under controlled conditions, often using colorimetric or fluorometric measurements.
  • Degradation assessment, such as the prevention of color loss or rancidity in products exposed to oxidation.

Why carry out a laboratory antioxidant analysis on your cosmetic products?

Performing antioxidant analysis in cosmetics allows us to assess the effectiveness of antioxidant additives and ensure the stability of formulas against environmental stresses (UV, pollution, oxidation).

Free radicals, responsible for the degradation of active ingredients and oxidative skin aging, require precise measurement of antioxidant capacity in order to:

  • Quality control of active antioxidant agent concentrations
    Analytical validation of antioxidant levels (vitamins, polyphenols, flavonoids, etc.) to ensure compliance with product specifications and guarantee the safety of cosmetic formulas.
  • Assessment of the oxidative stability of cosmetic matrices
  • Regulatory compliance assurance (EC No. 1223/2009) and claims validation
  • Analytical support for the preparation of safety dossiers and efficacy claim dossiers (anti-aging, anti-pollution, natural), in compliance with European requirements.
  • Formulation development support (R&D). Characterization of the antioxidant efficacy of new active ingredients or natural alternatives, optimization of dosages and ingredient synergies to formulate innovative and high-performance products.

The FILAB laboratory supports you in your antioxidant analysis needs

At FILAB, we offer additive analysis services. This includes antioxidant analysis: identification, measurement of antioxidant power, and antioxidant dosage.

Our antioxidant analysis services

The FILAB laboratory offers antioxidant analysis services in various types of formulations:

Our technical resources

Mass spectrometry

GC-MS HS-GC/MS

LC-QTOF-MS

ICP-MS

HPLC-MS et HPLC-MS/MS

Focus on our cosmetic antioxidant analysis

FILAB offers a comprehensive range of tests to characterize the antioxidant efficacy of your raw materials and formulations:

  • Overall antioxidant capacity: measures a sample's ability to neutralize free radicals and inhibit oxidation processes.
  • Lipid oxidation: assesses lipid oxidation processes, essential for the durability of vegetable oils and emulsions.
  • Oxidative degradation of formulations: identifies external factors (heat, UV, O₂) that accelerate the degradation of your formulas, allowing you to optimize product shelf life.
  • Antioxidant stability of cosmetic formulas: monitors the antioxidant capacity of your products over time and under real-life or accelerated aging conditions.

Our services associated with the analysis of antioxidant additives

Analysis and determination of 1,3-propanediol using chromatographic techniques: HS-GCMS, GCMS, HPLC-UV, etc.

Dosage de principes actifs : filtres solaires organiques et minéraux, vitamines...

Analysis of undesirable substances on raw materials and finished products: heavy metals, residual solvents, phthalates, bisphenol A, etc.

 

Analyses de substances indésirables sur Matières Premières et Produits finis : métaux lourds, solvants résiduels, phtalates, bisphénol A...

Dosage de conservateurs (phénoxyéthanol, parabens, chlorphenesin…) par HPLC-UV, HPLC-MSMS et GC-MS

Expertise sur des non-conformités : particules, dépôts, pics inconnus, dégradations de matériaux...

FILAB laboratory is able to provide services for the analysis of antioxidants in different formulations :

Our laboratory is able to provide analysis and determination services for the following antioxidants :

2,6-di-tert-butyl-4-methylphenol

(CAS 128-37-0)

BHT (Butylated Hydroxytoluene)

antioxidant

2,4,6-tri-tert-butylphenol

(CAS 732-26-3

2,4,6-TTBP

antioxidant

2,5-bis(5-tert-butylbenzoxanol-2-yl) thiophene

(CAS 7128-64-5)

Uvitex OB

optical brightener

 

Octadecyl-3-(3,5-di-tert-butyl-4-hydroxyphenyl) propionate

(CAS 2082-79-3)

Irganox 1076

antioxidant

Tris(2,4-di-tert-butylphenyl) phosphite

(CAS 31570-04-4)

Irgafos 168

antioxidant

Didodecyl 3,3’-thiodipropionate

(CAS 123-28-4)

Irganox PS800

antioxidant

2-hydroxy-4-(octyloxy) benzophenone

(CAS 1843-05-6)

Chimassorb 81

UV Absorbers /

stabilizer

Pentaerythritol tetrakis (3,5-di-tert-butyl-4-hydoxyhydrocinnamate) 

(CAS 6683-19-8)

Irganox 1010

antioxidant

1,3,5-trimethyl-2,4,6-tris (3,5-di-tert-butyl-4-hydroxybenzyl) benzene

(CAS 1709-70-2)

Irganox 1330

antioxidant

3,5-di-tert-butyl-4-hydroxyphenylpropionic acid

(CAS 20170-32-5)

Irganox degradate

antioxidant

Our services relating to the analysis of antioxidant additives

The filab advantages
A highly qualified team
A highly qualified team
Responsiveness in responding to and processing requests
Responsiveness in responding to and processing requests
A COFRAC ISO 17025 accredited laboratory
A COFRAC ISO 17025 accredited laboratory
(Staves available on www.cofrac.com - Accreditation number: 1-1793)
A complete analytical park of 5,200m²
A complete analytical park of 5,200m²
Tailor-made support
Tailor-made support
Video debriefing available with the expert
Video debriefing available with the expert
Thomas GAUTIER Head of Materials Department
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